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4.清瘟敗毒飲對人類禽流感之治療(Treatment of human influenza A (H5N1) infection with Ching-Wen-Bai-Du-Yin)

作者: Jen Shu Wanga, Kee Ching G. Jengb 雜誌期刊發表時日期: 2008-08-15

  期刊內容描述

Abstract
The World Health Organization (WHO) has recently documented 383 confirmed human cases of H5N1 infection with a mortality rate greater than 62.9% by May 2008. Although the surveillance of the bird and human populations for the pathogenic H5N1 virus is being conducted, sporadic avian influenza /H5N1 occurs in various places of the world and cause serious illness and death in humans. Clinical symptoms of H5N1 influenza are mainly involved with pneumonia with infiltrates, respiratory distress, tachypnea, and inspiratory crackles. Multiorgan failure with renal and cardiac dysfunction is also common. Therefore, understanding its pathology, transmission route, clinical features, and treatments would help us preparing for the prevention and management of this infection. The Ching-Wen-Bai-Du-Yin (anti-pyretic and anti-toxic soup) is formulated for the treatment of symptoms of flu or pestilence in the past. Ching-wen-bai-du-yin (CWBDY) consists of gypsum, Rehmanniae Radix, rhinoceros (now, buffalo) horn, Coptidis rhizoma, Fructus Gardenia Jasminoides, Radix Platycodi Grandiflori, Radix Scutellariae Baicalensis, Anemarrhena Rhizome, Radix Paeonia Lactiflora, Fructus Forsythiae Suspensae, Radix Scrophulariae Ningpoensis, Radix Glycyrrhizae Uralensis, Cortex Moutan Radicis, and Herba Loaphatheri Gracilis. The formula was targeted for antipyretic, anti-inflammatory, analgesic, sedative, anti-bacterial, antiviral, hepatoprotection, detoxification, tonic and diuretic effects. The antipyretic and antiinflammatory may reduce the pulmonary injury and inflammation by H5N1 virus. In addition, other effects by CWBDY may be complimentary to the current therapy.





 


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